Methanol - Chromatography & Reagent Applications
Methanol is a primary polar solvent widely used as a mobile‑phase component in HPLC and LC-MS, especially for reversed‑phase separations.It dissolves a broad range of analytes and offers low UV cut‑off, supporting UV, DAD, and MS detection without excessive baseline noise.In synthesis labs, methanol acts as a reagent and solvent for esterifications, transesterifications, and quenching reactions.High‑purity grades reduce background in analytical assays, making it suitable for calibration standard preparation and instrument rinsing.
